Immune response to a secondary stimulus with leptospira canicola and infectious canine hepatitis in beagles exposed to sr90 lf 29 clapper we sanchez a levy j pmid 5296567 pubmed indexed for medline mesh terms animals antibody formation radiation effects dogs hepatitis animal immunology leptospira interrogans serovar canicola. The secondary immune response to l canicola and ich virus was depressed in beagle dogs which had inhaled particles of sr90 1 2 days and 7 days before the immune stimulus the initial body burden was 31 46 microcuries per kilogram the peak titre was reached for both antigens within eleven days in both control and exposed dogs. A conserved region of leptospiral immunoglobulin like a and b proteins as a dna vaccine elicits a prophylactic immune response against leptospirosis enhanced type i immune response to a hepatitis b dna vaccine by formulation with calcium or aluminum pathogenic leptospira species express surface exposed proteins belonging to the . Strains of canine distemper canine adenovirus type 2 cav 2 canine parainfluenza and canine parvovirus type 2b propagated in cell line tissue cultures the diluent is canine parvovirus vaccine leptospira canicola icterohaemorrhagiae bacterinthe cav 2 fraction cross protects against respiratory infection caused by infectious canine hepatitis
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